Técnicas de Edición Genómica

Referencias:
1CRISPR/Cas9 cleavage of viral DNA efficiently suppresses hepatitis B virus(2015)
2.Efficient inhibition of duck hepatitis B virus DNA by the CRISPR/Cas9 system (2017)
3.Liver-Targeted Anti-HBV Single-Stranded Oligonucleotides with Locked Nucleic Acid Potently Reduce HBV Gene Expression In Vivo (2018)
4. In vivo reduction of hepatitis B virus antigenemia and viremia by antisense oligonucleotides. (2016)

Terapia con Stem Cells en Hepatitis B

Referencias :

1.Human Adipose-Derived Mesenchymal Stem Cells Are Resistant to HBV Infection during Differentiation into Hepatocytes in Vitro (2014)

2.Infected hematopoietic stem cells and with integrated HBV DNA generate defective T cells in chronic HBV infection patients(2014)

TRASNGÉNICO VEGETAL

Referencia:
1. Study of the immunogenicity of hepatitis B surface antigen synthesized in transgenic potato plants with increased biosafety.(2015)

ADN Recombinante

 Referencias:
1.  Expresión y purificación del antígeno preS1/2 y su utilidad en el estudio de la patogeniade la infección por el virus de la hepatitis B (2013)
2. Recombinant covalently closed circular DNA of hepatitis B virus induces long-term viral persistence with chronic hepatitis in a mouse model.(2018)

3. Hepatitis B virus infection (2018)

Southern Blot

Referencias:

1.A southern blot assay for detection of hepatitis B virus covalently closed circular DNA from cell cultures.(2013)

Una prueba de Reacción en Cadena de la Polimerasa

Referencia:

Validación de PCR para el diagnostico de HepatitisB (2013)

Prueba de Tamizaje y Confirmatoria

Referencia:

1. Prevalencia de tamizaje deHepatitis y factores asociados paracoinfección con otros marcadoresinfecciosos en banco de sangre. (2013) 

2. Effectiveness of hepatitis B rapid tests toward linkage-to-care: results of a randomized, multicenter study. (2016)
3. One or two serological assay testing strategy for diagnosis of HBV and HCV infection? The use of predictive modelling (2017)